Topic information for: BRCA2
Beyond The Shock® Educational Video
In Subchapter 3.1, “Growth of Cancer”, we discussed the role of receptors in cancer cells. Doctors seek to determine what causes certain types of cancer to progress by...
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Treatment at the end of this week! Very nervous! I am booked for chemo unless my gene study proves other wise. Has anyone else been involved in the gene study?
Asked by anonymous
Learning About Breast Cancer- View all 8 answers
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anonymous
Learning About Breast Cancer
Some questions. If one or both of you have had a lumpectomy or a partial mastectomy, I have not heard any mention of radiation which is standard care for breast conservation. Did I understand the surgery correctly?
Are y'all talking about the OncotypeDX test sent off to determine ER,PR, Her2...Comment 0Some questions. If one or both of you have had a lumpectomy or a partial mastectomy, I have not heard any mention of radiation which is standard care for breast conservation. Did I understand the surgery correctly?
Are y'all talking about the OncotypeDX test sent off to determine ER,PR, Her2 positive or negative and the percentage of recurrence and the benefit of chemo? I may be wrong and one of the girls who has done this will clarify it, but if you have lymph node involvement I think chemo is standard. I hope some of the women who post regularly that have had this scenerio in their treatment will jump in. The process is slow when waiting but I would call the doctor with any questions to clarify what options are ahead . My chemo was to be after the radiation but my DX test showed no benefit worth the risks. Good luck and take care. Jo :-D -
anonymous
Survivor since 2012
Yes, iwas tested for the BRC1 and BRCA2 gene mutations, if that's what you mean. Mine came pack positive for BRCA2. My Oncotype also was very high, adding to the chance of recurrence. It sure wasn't what I wanted, but there's nothing I can do about it except remain diligent and have frequent...
Comment 0Yes, iwas tested for the BRC1 and BRCA2 gene mutations, if that's what you mean. Mine came pack positive for BRCA2. My Oncotype also was very high, adding to the chance of recurrence. It sure wasn't what I wanted, but there's nothing I can do about it except remain diligent and have frequent checkups.
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Brca2 gene..anyone with this?
Asked by anonymous
Learning About Breast Cancer- View all 7 answers
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anonymous
Learning About Breast Cancer
I'm brca 2 positive. Decided to have a double mastectomy with reconstruction. Didn't need rads or chemo. I'm not sorry that I was aggressive. I don't have to worry about breast cancer again.
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anonymous
Learning About Breast Cancer
Hi Melissa, I had a mastectomy in 2006, and will have a mastectomy on the left side as a preventative, so that I won't get cancer again! You have a great positive attitude! Good luck in future..
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Been advised that I should B tested for the BRCA gene,Im 19.My nan had breast cancer,my dad&other men had prostrate cancer.I was told breast&prostate cancer R the genes its related 2, R there any others?Want some advice,scared of finding I have the gene!
Asked by anonymous
Learning About Breast Cancer- View all 5 answers
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anonymous
Survivor since 2007
Genine,
Taking this test is a look into your future. If you have this gene, the type of breast cancer is one that strikes younger women and is aggressive. BUT.... there is the huge chance you will not have this gene. Does your Mom have this gene, any of her sisters been tested? There are...Comment 1Genine,
Taking this test is a look into your future. If you have this gene, the type of breast cancer is one that strikes younger women and is aggressive. BUT.... there is the huge chance you will not have this gene. Does your Mom have this gene, any of her sisters been tested? There are specifics in suspecting this gene is in your family. Turn your fear into bravery and get some genetic counceling. The enormity of this feels like it is looming over you.... grab that fear and charge head-long into it. You ARE stronger than you think. A large reason for your fear is the unknown. IF.... and it is a big IF, you do have this gene, you CAN do something to save yourself from a whole bunch of future grief.
Knowledge truly is power. Hang in there and fight like a WOMAN! Take care, Sharon -
anonymous
Learning About Breast Cancer
After finding out I have breast cancer - I did have the genetic test and was positive brca2
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I have IDC. My uncle had melanoma and colon cancer. No other family cancer. Does that raise my risk of BRCA 1 and 2?
Asked by anonymous
Learning About Breast Cancer-
anonymous
Industry Provider
BRCA 1 and 2 are uncommon mutations. Only 2-3% of women with breast cancer have them. However, it is useful to know if you have the gene in your family because their risk of getting breast cancer in their lifetime is 60%, as compared to 18% for someone without the mutation. Doctors use the...
Comment 1BRCA 1 and 2 are uncommon mutations. Only 2-3% of women with breast cancer have them. However, it is useful to know if you have the gene in your family because their risk of getting breast cancer in their lifetime is 60%, as compared to 18% for someone without the mutation. Doctors use the following aid to assist in their decisions to test for the mutation.
https://www.myriadpro.com/brca-risk-calculator
The predictions rely strongly on breast cancer family history
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anonymous
Stage 4 Patient
No, not necessarily. Approx. 75% of women diagnosed with breast cancer have no family history. I have IDC as well and have no family history of cancer. Regardless of that, I do believe it's a good idea for for women with breast cancer to have the BRACA test. I had the test performed and it was...
Comment 1No, not necessarily. Approx. 75% of women diagnosed with breast cancer have no family history. I have IDC as well and have no family history of cancer. Regardless of that, I do believe it's a good idea for for women with breast cancer to have the BRACA test. I had the test performed and it was negative.
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How does genetic testing help
Asked by anonymous
Patient-
anonymous
Survivor since 2003
Genetic testing helps if you have a family history of breast cancer and your brca1 and brca2 (the two genes that are currently being tested) is positive it makes it easier for family members to receive preventive care and monitoring male or female , for any of the reproductive types of cancers....
Comment 2Genetic testing helps if you have a family history of breast cancer and your brca1 and brca2 (the two genes that are currently being tested) is positive it makes it easier for family members to receive preventive care and monitoring male or female , for any of the reproductive types of cancers. Breast ovarian prostrate or testicular. As for a women with breast cancer if her gene testing is positive then it gives her other choices to think about. Mastectomy over lumpectomy. Hysterectomy with removal her ovaries. They also might want to treat her a little more aggressive with chemo and radiation. Gene testing is very expensive when I had it done in 2008 it cost $3000 I paid 10% $300 it was covered by my insurance as I met the criteria being 43 when first diagnosed and having a strong family history of breast cancer and prostate cancer. My results were negative go figure. I did it for my sister and my daughter. They could have been monitored more closely if it came back positive. Having the gene testing does not in any way say you will or will not get breast cancer it is just another tool to help make decisions for your course of treatment. Hope that helps
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anonymous
Survivor since 2003
Genetic testing helps if you have a family history of breast cancer and your brca1 and brca2 (the two genes that are currently being tested) is positive it makes it easier for family members to receive preventive care and monitoring male or female , for any of the reproductive types of cancers....
Comment 0Genetic testing helps if you have a family history of breast cancer and your brca1 and brca2 (the two genes that are currently being tested) is positive it makes it easier for family members to receive preventive care and monitoring male or female , for any of the reproductive types of cancers. Breast ovarian prostrate or testicular. As for a women with breast cancer if her gene testing is positive then it gives her other choices to think about. Mastectomy over lumpectomy. Hysterectomy with removal her ovaries. They also might want to treat her a little more aggressive with chemo and radiation. Gene testing is very expensive when I had it done in 2008 it cost $3000 I paid 10% $300 it was covered by my insurance as I met the criteria being 43 when first diagnosed and having a strong family history of breast cancer and prostate cancer. My results were negative go figure. I did it for my sister and my daughter. They could have been monitored more closely if it came back positive. Having the gene testing does not in any way say you will or will not get breast cancer it is just another tool to help make decisions for your course of treatment. Hope that helps
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My mother is having a double mastectomy. Post surgery, what are the advantages of her doing genetic testing? Thanks!
Asked by anonymous
Learning About Breast Cancer-
anonymous
Survivor since 2003
Hi Megan genetic testing for the BRCA 1 and BRCA 2 are used post surgery as a further test to determine the treatment course. A positive result tells you that you carry the breast cancer gene the doctor might want to be more aggressive with her treatment and maybe suggesting removal of her...
Comment 1Hi Megan genetic testing for the BRCA 1 and BRCA 2 are used post surgery as a further test to determine the treatment course. A positive result tells you that you carry the breast cancer gene the doctor might want to be more aggressive with her treatment and maybe suggesting removal of her ovaries. A positive results will also help the family members male and female siblings and children get better monitoring and screening like earlier mammograms then age 50 or blood test and ultra sounds to screen for ovarian, prostrate and testicular cancers A negative results says that one doesn't carry the breast cancer gene but they are only testing two genes there maybe more that they are unable to test at this time. A positive or negative result does not mean you will or will not get cancer. It is just saying the gene is or is not present.
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anonymous
Learning About Breast Cancer
I had the BRCA testing 2 years ago after my surgery. Now my daughter and nieces are having trouble being carried by health insurance for "per-existing condition" be sure to consult this concern with her oncologist.
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Is breast cancer hereditary?
Asked by anonymous
Family Member or Loved One-
anonymous
Survivor since 2011
It can be. See if you can get the brace test to see if you or she is positive.
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anonymous
Stage 4 Patient
It can be Randall, but in over 75% of women diagnosed with breast cancer...there is no family history at all. I wasn't aware of this until I was diagnosed last year. I had no family history of breast cancer. I do think it's a good idea to have the genetic BRACA testing performed. If a woman...
1 comment 0It can be Randall, but in over 75% of women diagnosed with breast cancer...there is no family history at all. I wasn't aware of this until I was diagnosed last year. I had no family history of breast cancer. I do think it's a good idea to have the genetic BRACA testing performed. If a woman tests positive for the gene, she will need to look at more options in her treatment, and there are several more things to be considered as well in a positive result.
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Anyone here have the BRCA2 gene?
Asked by anonymous
Learning About Breast Cancer-
anonymous
Learning About Breast Cancer
I was first diagnosed with breast cancer in 1993 and it was DCIS on the left. I had a lumpectomy and radiation. Last February 2011 they found something on my mammo so I had a biopsy done which turned out to be a new cancer on the left side of DCIS again. They tested me and I am positive for...
4 comments 0I was first diagnosed with breast cancer in 1993 and it was DCIS on the left. I had a lumpectomy and radiation. Last February 2011 they found something on my mammo so I had a biopsy done which turned out to be a new cancer on the left side of DCIS again. They tested me and I am positive for BRCA2. My sister died from breast cancer and her granddaughter (age 27) was diagnosed with stage 2 cancer and she had BRCA2 as well. After having a bilateral mastectomy this time around, they also discovered I had breast cancer in the right breast which was ICLS. They are encouraging me to have my ovaries removed soon as the gene increases my chances for getting ovarian cancer. Rely on your doctors and other experts as your emotions can get out of control when you start listening to a lot of other people.
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anonymous
Survivor since 2012
Yes, I have the BRCA2 gene mutation. I first had breast cancer in 2000, at age 44. It was Stage 1B, no node involvement, DCIS with slight ductal invasion. I had a mastectomy and radiation. I was diagnosed in October 2011 with cancer in my remaining breast. It's not a recurrence but a new...
Comment 0Yes, I have the BRCA2 gene mutation. I first had breast cancer in 2000, at age 44. It was Stage 1B, no node involvement, DCIS with slight ductal invasion. I had a mastectomy and radiation. I was diagnosed in October 2011 with cancer in my remaining breast. It's not a recurrence but a new cancer. Stage 2A, invasive ductal, with no node involvement but more aggressive and a larger tumor this time around. Given these facts, I was tested shortly after my second diagnosis in October 2011.
Do you have more specific questions? I can tell you that your siblings and children, male and female, have a 50:50 chance of having the mutation. My one sibling, a sister in her early 50's, has tested positive. If inherited, there are increased risks for breast and other forms of cancer in both males and females, more so for females. First piece of advice: do not go on the internet and start searching. Rely on your doctors, geneticists, and other experts in the field. I'll be happy to answer any other questions or concerns you may have.
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I have infiltrating DC. I tested pos. for BRCA gene. I will be having bilateral mastectomy on thurs. with reconstruction. I was told I was a candidate for nipple sparing mastectomy & am considering this. Any thoughts or opinions?
Asked by anonymous
Learning About Breast Cancer- View all 5 answers
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anonymous
Learning About Breast Cancer
I had a nipple/skin sparing mastectomy last August for IDC. Postoperatively, I had pain for several weeks. My PS wouldn't give me anymore pain pills. The implant goes behind your pectoris (chest wall muscle). Your muscle and skin have to stretch to accomodate the implant
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anonymous
Learning About Breast Cancer
My surgery was a success. The PS did such a good job. Nothing can prepare you to see your new breast/s and then they are numb and way too firm. I do believe this technique is the way to go for the most natural look. Scars are less disfiguring. Hope your journey foes well
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What is the difference if BRCA1 or BRCA2 is identified as the mutation?
Asked by anonymous
Learning About Breast Cancer
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